The transforaminal epidural block differs only slightly from the standard epidural. The only difference is that the needle is introduced next to the exiting nerve root. In cases of nerve root complaints, this is more advantageous than the standard epidural because the medication reaches the affected nerve root more precisely.

The procedure is guided by X-ray, allowing for very precise positioning of the needle. In cases of disc herniation and nerve root compression epidurolysis is more effective, although it is a much more complex intervention.

In simple cases, transforaminal epidural is generally recommended, while in more severe, chronic cases, or in operated spines, epidurolysis is more effective.